Product ID:FENTANYL CITRATE INJECTION USP, 9094
MSDS Date:06/03/1991
FSC:6505
NIIN:01-222-8396
MSDS Number: BVBMF

ABBOTT LABORATORIES

HOSPITAL PRODUCTS DIV
NORTH CHICAGO, IL 60064-3502
US

Emergency Phone: 708-937-6100

Info Phone: 708-937-6100

Cage: 70048

ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV

NORTH CHICAGO, IL 60064-3500 US

Telephone: 847-935-7155

Cage: 70048

PROPIONANILIDE, N-(1-PHENETHYL-4-PIPERIDYL)-, CITRATE

CAS: 990-73-8

RTECS: UE5600000

OSHA PEL N/K

ACGIH TLV: N/K

PROPANAMIDE CITRATE)

RTECS: 9999999ZZ

OSHA PEL N/K

ACGIH TLV: N/K

EFFECTS WHICH IF NOT TREATED CAN LEAD TO

RTECS: 9999999ZZ

OSHA PEL N/K

ACGIH TLV: N/K

AMTS OF WATER FOR AT LST 15 MINS. IF IRRIT

RTECS: 9999999ZZ

OSHA PEL N/K

ACGIH TLV: N/K

CALL MD IMMEDIATELY .

RTECS: 9999999ZZ

OSHA PEL N/K

ACGIH TLV: N/K

LD50 LC50 Mixture:LD50 (ORAL,RAT): 18-136 MG/KG.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:SPECIAL TARGET ORGAN EFTS:FENTANYL
CITRATE IS POTENT NARCOTIC ANALGESIC THAT IS 100 TIMES MORE POTENT
THAN MORPHINE. IT IS USED THERAPEUTICALLY TO PRDCE ANALGESIA (PAIN
RELEIF) & SEDATION. FENTANYL CI TRATE CAN CAUSE RESP DEPRESS,
REDUCED HEART RATE & MUSCLE RIGIDITY. IN REPROD STUDIES IN RATS,
FENTANYL(EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT.
Effects of Overexposure:HLTH HAZ: CITRATE ADMIN RSLTD IN DECREASE IN
PREGNANCY RATE AT 12.5 TIMES HUMAN DOSE & AN EMBRYOCIDAL EFT AT 0.3
TIMES HUMAN DOSE. FENTANYL CITRATE CAN PRODUCE DRUG DEPENDENCE OF
MORPHINE TYPE & HAS P OTNTL FOR BEING ABUSED. SIGNS & SYMPS OF
OVEREXP: CLINICALLY, OVEREXP CAN PRDCE RESP DEPRESS (BRTHG
DFCLTYS), (SUPDAT)
Medical Cond Aggravated by Exposure:DATA SUGGEST CONDITIONS ASSOCIATED
WITH IMPAIRED RESPIRATION, LIVER OR KIDNEY DYSFUNCTION, HEART
DISEASE AND CONCURRENT USE OF CNS DEPRESSANT DRUGS.

First Aid:REMOVE FROM SOURCE OF EXPOS. SKIN: FLUSH W/COPIOUS AMTS OF
WATER. IF IRRIT PERSISTS/SIGNS OF TOX OCCUR, SEEK MED ATTN. INHAL:
REMOVE FROM EXPOS. SUPPORT BRTHG (GIVE ARTF RESP/OXYGEN) SPECIFIC
N ARC ANTAGONISTS, E.G., NALORPHINE HYDROBROMIDE OR NALOXONE
HYDROCHLORIDE, ARE ANTIDOTES FOR RESP DEPRESS PRDCED BY FENTANYL
CITRATE. PROVIDE SYMP/SUPPORTIVE CARE AS NEC. EYE: FLUSH W/COPIOUS
(ING 4)

Flash Point:NON-FLAMMABLE
Extinguishing Media:USE MEDIA SUITABLE FOR SURROUNDING FIRE CONDITIONS
.
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA AND FULL
PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:NONE.

Spill Release Procedures:ABSORB WITH SUITABLE MATERIAL, FLUSH WITH
WATER AND METHANOL.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:NONE.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.

Respiratory Protection:NONE REQUIRED. WEAR NIOSH/MSHA APPROVED
RESPIRATOR APPROPRIATE FOR EXPOSURE OF CONCERN .
Ventilation:NO SPECIAL PROVISIONS REQUIRED.
Protective Gloves:RUBBER GLOVES.
Eye Protection:SAFETY GLASSES.
Other Protective Equipment:NOT APPLICABLE.
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
PH:4.0-7.5.EFTS OF OVEREXPOSURE: REDUCED HEART RATE & MUSCLE RIGIDITY.
OTHER ADVERSE RXNS INCL CHANGES IN BLOOD PRESS, DIZZ, BLURRED
VISION, NAUS, EMESIS, LARYNGOSPASM & PERSPIRATION. OPIOID ANALGESIC
S PRDCE EUPHORIA, MIOSIS (CONSTRICTION OF PUPILS), REDUCED HEART
RATE & BRONCHOCONSTRICTION. OVERDOSE PRDCES SAME(ING 3)

Boiling Pt:B.P. Text:WATER
Spec Gravity:WATER
pH:SUPDAT
Solubility in Water:AQUEOUS SOLUTION
Appearance and Odor:CLEAR LIQUID.
Percent Volatiles by Volume:NEGLIG

Stability Indicator/Materials to Avoid:YES
NONE.
Stability Condition to Avoid:NONE.
Hazardous Decomposition Products:WHEN HEATED TO DECOMPOSITION, IT EMITS
TOXIC FUMES OF OXIDES OF NITROGEN.

Waste Disposal Methods:DISPOSE OF SOLUTION IN SEWER. BURY IN LANDFILL.
DISPOSE OF IN ACCORDANCE WITH FEDERAL, STATE AND LOCAL REGULATIONS
.

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